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MUC16 suppresses human and murine innate immune responses
OBJECTIVE: MUC16, the mucin that contains the CA125 epitopes, suppresses the cytolytic responses of human NK cells and inhibits the efficacy of therapeutic antibodies. Here, we provide further evidence of the regulatory role of MUC16 on human and murine NK cells and macrophages. METHODS. Target cell...
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| Publicado no: | Gynecol Oncol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8327469/ https://ncbi.nlm.nih.gov/pubmed/30626487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2018.12.023 |
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