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Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells
T lymphoma cells may constitutively express PD-1 and PD-L1. The relative role of PD-1 and PD-L1 in T lymphoma is incompletely understood. We report here that PD-1(+) PDL-1(+) human T lymphoma cells exhibit constitutive hyperactivation of the TCR signaling and do not respond to PD-L1-mediated suppres...
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| Veröffentlicht in: | Cell Immunol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8327398/ https://ncbi.nlm.nih.gov/pubmed/34157461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2021.104397 |
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