Chemotherapy-Induced Degradation of Glycosylated Components of the Brain Extracellular Matrix Promotes Glioblastoma Relapse Development in an Animal Model

Adjuvant chemotherapy with temozolomide (TMZ) is an intrinsic part of glioblastoma multiforme (GBM) therapy targeted to eliminate residual GBM cells. Despite the intensive treatment, a GBM relapse develops in the majority of cases resulting in poor outcome of the disease. Here, we investigated off-t...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Tsidulko, Alexandra Y., Shevelev, Oleg B., Khotskina, Anna S., Kolpakova, Mariia A., Suhovskih, Anastasia V., Kazanskaya, Galina M., Volkov, Alexander M., Aidagulova, Svetlana V., Zavyalov, Evgenii L., Grigorieva, Elvira V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327169/
https://ncbi.nlm.nih.gov/pubmed/34350124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.713139
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