Conventional Anti-glioblastoma Chemotherapy Affects Proteoglycan Composition of Brain Extracellular Matrix in Rat Experimental Model in vivo

Temozolomide (TMZ) is a conventional chemotherapy drug for adjuvant treatment of glioblastoma multiforme (GBM), often accompanied by dexamethasone (DXM) to prevent brain oedema and alleviate clinical side effects. Here, we aimed to investigate an ability of the drugs to affect normal brain tissue in...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Tsidulko, Alexandra Y., Bezier, Cynthia, de La Bourdonnaye, Gabin, Suhovskih, Anastasia V., Pankova, Tatiana M., Kazanskaya, Galina M., Aidagulova, Svetlana V., Grigorieva, Elvira V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176078/
https://ncbi.nlm.nih.gov/pubmed/30333749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01104
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