Heparan Sulfate Biosynthetic System Is Inhibited in Human Glioma Due to EXT1/2 and HS6ST1/2 Down-Regulation

Heparan sulfate (HS) is an important component of the extracellular matrix and cell surface, which plays a key role in cell–cell and cell–matrix interactions. Functional activity of HS directly depends on its structure, which determined by a complex system of HS biosynthetic enzymes. During malignan...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ushakov, Victor S., Tsidulko, Alexandra Y., de La Bourdonnaye, Gabin, Kazanskaya, Galina M., Volkov, Alexander M., Kiselev, Roman S., Kobozev, Vyacheslav V., Kostromskaya, Diana V., Gaytan, Alexey S., Krivoshapkin, Alexei L., Aidagulova, Svetlana V., Grigorieva, Elvira V.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713271/
https://ncbi.nlm.nih.gov/pubmed/29104277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18112301
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