Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway

The presence of gastric cancer stem cells (GCSCs) marks the onset of gastric carcinoma. The sonic hedgehog (SHH) pathway plays a vital role in the maintenance of GCSC characteristics. Apatinib has been approved in China for advanced gastric cancer (GC) treatment. However, whether apatinib can target...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Cao, Wanshuang, Li, Yuan, Sun, Hongliang, Yang, Chenying, Zhu, Jianyun, Xie, Chunfeng, Li, Xiaoting, Wu, Jieshu, Geng, Shanshan, Wang, Lu, Sun, Liangfei, Geng, Guozhu, Han, Hongyu, Zhong, Caiyun
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8326764/
https://ncbi.nlm.nih.gov/pubmed/34350176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.679806
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