Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway

The presence of gastric cancer stem cells (GCSCs) marks the onset of gastric carcinoma. The sonic hedgehog (SHH) pathway plays a vital role in the maintenance of GCSC characteristics. Apatinib has been approved in China for advanced gastric cancer (GC) treatment. However, whether apatinib can target...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Dev Biol
Prif Awduron: Cao, Wanshuang, Li, Yuan, Sun, Hongliang, Yang, Chenying, Zhu, Jianyun, Xie, Chunfeng, Li, Xiaoting, Wu, Jieshu, Geng, Shanshan, Wang, Lu, Sun, Liangfei, Geng, Guozhu, Han, Hongyu, Zhong, Caiyun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Cell and Developmental Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8326764/
https://ncbi.nlm.nih.gov/pubmed/34350176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.679806
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