Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway

The presence of gastric cancer stem cells (GCSCs) marks the onset of gastric carcinoma. The sonic hedgehog (SHH) pathway plays a vital role in the maintenance of GCSC characteristics. Apatinib has been approved in China for advanced gastric cancer (GC) treatment. However, whether apatinib can target...

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Foilsithe in:Front Cell Dev Biol
Main Authors: Cao, Wanshuang, Li, Yuan, Sun, Hongliang, Yang, Chenying, Zhu, Jianyun, Xie, Chunfeng, Li, Xiaoting, Wu, Jieshu, Geng, Shanshan, Wang, Lu, Sun, Liangfei, Geng, Guozhu, Han, Hongyu, Zhong, Caiyun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Cell and Developmental Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8326764/
https://ncbi.nlm.nih.gov/pubmed/34350176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.679806
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