Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway

The presence of gastric cancer stem cells (GCSCs) marks the onset of gastric carcinoma. The sonic hedgehog (SHH) pathway plays a vital role in the maintenance of GCSC characteristics. Apatinib has been approved in China for advanced gastric cancer (GC) treatment. However, whether apatinib can target...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Cao, Wanshuang, Li, Yuan, Sun, Hongliang, Yang, Chenying, Zhu, Jianyun, Xie, Chunfeng, Li, Xiaoting, Wu, Jieshu, Geng, Shanshan, Wang, Lu, Sun, Liangfei, Geng, Guozhu, Han, Hongyu, Zhong, Caiyun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8326764/
https://ncbi.nlm.nih.gov/pubmed/34350176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.679806
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