TRAIL-receptor 2—a novel negative regulator of p53

TNF-related apoptosis-inducing ligand (TRAIL) receptor 2 (TRAIL-R2) can induce apoptosis in cancer cells upon crosslinking by TRAIL. However, TRAIL-R2 is highly expressed by many cancers suggesting pro-tumor functions. Indeed, TRAIL/TRAIL-R2 also activate pro-inflammatory pathways enhancing tumor ce...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Willms, Anna, Schupp, Hella, Poelker, Michelle, Adawy, Alshaimaa, Debus, Jan Frederik, Hartwig, Torsten, Krichel, Tim, Fritsch, Jürgen, Singh, Steven, Walczak, Henning, von Karstedt, Silvia, Schäfer, Heiner, Trauzold, Anna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325694/
https://ncbi.nlm.nih.gov/pubmed/34333527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04048-1
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