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Getting TRAIL back on track for cancer therapy
Unlike other members of the TNF superfamily, the TNF-related apoptosis-inducing ligand (TRAIL, also known as Apo2L) possesses the unique capacity to induce apoptosis selectively in cancer cells in vitro and in vivo. This exciting discovery provided the basis for the development of TRAIL-receptor ago...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131183/ https://ncbi.nlm.nih.gov/pubmed/24948009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.81 |
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