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Getting TRAIL back on track for cancer therapy

Unlike other members of the TNF superfamily, the TNF-related apoptosis-inducing ligand (TRAIL, also known as Apo2L) possesses the unique capacity to induce apoptosis selectively in cancer cells in vitro and in vivo. This exciting discovery provided the basis for the development of TRAIL-receptor ago...

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Autori principali: Lemke, J, von Karstedt, S, Zinngrebe, J, Walczak, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131183/
https://ncbi.nlm.nih.gov/pubmed/24948009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.81
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