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TRAIL-receptor 2—a novel negative regulator of p53
TNF-related apoptosis-inducing ligand (TRAIL) receptor 2 (TRAIL-R2) can induce apoptosis in cancer cells upon crosslinking by TRAIL. However, TRAIL-R2 is highly expressed by many cancers suggesting pro-tumor functions. Indeed, TRAIL/TRAIL-R2 also activate pro-inflammatory pathways enhancing tumor ce...
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| Publicat a: | Cell Death Dis |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8325694/ https://ncbi.nlm.nih.gov/pubmed/34333527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04048-1 |
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