FBXO16-mediated hnRNPL ubiquitination and degradation plays a tumor suppressor role in ovarian cancer

Heterogeneous nuclear ribonucleoprotein L (hnRNPL) is a type of RNA binding protein that highly expressed in a variety of tumors and plays a vital role in tumor progression. However, its post-translational regulation through ubiquitin-mediated proteolysis and the cellular mechanism responsible for i...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Ji, Mei, Zhao, Zhao, Li, Yue, Xu, Penglin, Shi, Jia, Li, Zhe, Wang, Kaige, Huang, Xiaotian, Ji, Jing, Liu, Wei, Liu, Bin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325689/
https://ncbi.nlm.nih.gov/pubmed/34333526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04040-9
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