hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition

Long INterspersed Element one (LINE-1, or L1), is a widely distributed, autonomous retrotransposon in mammalian genomes. During retrotransposition, L1 RNA functions first as a dicistronic mRNA and then as a template for cDNA synthesis. Previously, we defined internal ribosome entry sequences (IRESs)...

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Bibliografske podrobnosti
Main Authors: Peddigari, Suresh, Li, Patrick Wai-Lun, Rabe, Jennifer L., Martin, Sandra L.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592465/
https://ncbi.nlm.nih.gov/pubmed/23161687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1075
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