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Racemization-free synthesis of Nα-2-thiophenoyl-phenylalanine-2-morpholinoanilide enantiomers and their antimycobacterial activity

Nα-2-thiophenoyl-d-phenylalanine-2-morpholinoanilide (MMV688845, IUPAC: N-(1-((2-morpholinophenyl)amino)-1-oxo-3-phenylpropan-2-yl)thiophene-2-carboxamide) from the Pathogen Box(®) library (Medicines for Malaria Ventures, MMV) is a promising lead compound for antimycobacterial drug development. Two...

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Bibliografiske detaljer
Udgivet i:Amino Acids
Main Authors: Mann, Lea, Lang, Markus, Schulze, Philipp, Halz, Jan Henrik, Csuk, René, Hoenke, Sophie, Seidel, Rüdiger W., Richter, Adrian
Format: Artigo
Sprog:Inglês
Udgivet: Springer Vienna 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325651/
https://ncbi.nlm.nih.gov/pubmed/34259925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-021-03044-1
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