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Pharmacokinetics of ketoprofen enantiomers after different doses of the racemate.

The pharmacokinetics of the enantiomers of ketoprofen after oral administration of 12.5 mg, 25 mg and 50 mg and i.v. administration of 50 mg racemic ketoprofen to 24 healthy subjects were investigated. The AUC values of R- (r2 = 0.929) and S-ketoprofen (r2 = 0.930) were proportional to dose. The abs...

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Detalhes bibliográficos
Main Authors: Geisslinger, G, Menzel, S, Wissel, K, Brune, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1365030/
https://ncbi.nlm.nih.gov/pubmed/8527271
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