The influence of renal function on the pharmacokinetics of unchanged and acyl-glucuroconjugated ketoprofen enantiomers after 50 and 100 mg racemic ketoprofen

1. To study the effect of renal dysfunction on the pharmacokinetics of ketoprofen (KT), and the possibility of saturation of clearance with elevation of dose, single 50 and 100 mg doses of racemic ketoprofen were administered in a cross-over fashion to seven patients (creatinine clearance, CL(CR), 6...

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Bibliografiske detaljer
Main Authors: SKEITH, KJ, DASGUPTA, M, LANGE, R, JAMALI, F
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 1996
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042652/
https://ncbi.nlm.nih.gov/pubmed/8864313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.03864.x
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