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Widespread remodeling of the m(6)A RNA-modification landscape by a viral regulator of RNA processing and export
N(6)-methyladenosine (m(6)A) is the most abundant internal messenger RNA (mRNA) modification, contributing to the processing, stability, and function of methylated RNAs. Methylation occurs in the nucleus during pre-mRNA synthesis and requires a core methyltransferase complex consisting of METTL3, ME...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8325250/ https://ncbi.nlm.nih.gov/pubmed/34282019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2104805118 |
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