Targeting the m(6)A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication

N(6)-methyladenosine (m(6)A) is an abundant internal RNA modification, influencing transcript fate and function in uninfected and virus-infected cells. Installation of m(6)A by the nuclear RNA methyltransferase METTL3 occurs cotranscriptionally; however, the genomes of some cytoplasmic RNA viruses a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Burgess, Hannah M., Depledge, Daniel P., Thompson, Letitia, Srinivas, Kalanghad Puthankalam, Grande, Rebecca C., Vink, Elizabeth I., Abebe, Jonathan S., Blackaby, Wesley P., Hendrick, Alan, Albertella, Mark R., Kouzarides, Tony, Stapleford, Kenneth A., Wilson, Angus C., Mohr, Ian
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247602/
https://ncbi.nlm.nih.gov/pubmed/34168039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.348320.121
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker