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Widespread remodeling of the m(6)A RNA-modification landscape by a viral regulator of RNA processing and export

N(6)-methyladenosine (m(6)A) is the most abundant internal messenger RNA (mRNA) modification, contributing to the processing, stability, and function of methylated RNAs. Methylation occurs in the nucleus during pre-mRNA synthesis and requires a core methyltransferase complex consisting of METTL3, ME...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Srinivas, Kalanghad Puthankalam, Depledge, Daniel P., Abebe, Jonathan S., Rice, Stephen A., Mohr, Ian, Wilson, Angus C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325250/
https://ncbi.nlm.nih.gov/pubmed/34282019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2104805118
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