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CRISPR/Cas9-engineered Drosophila knock-in models to study VCP diseases
Mutations in Valosin Containing Protein (VCP) are associated with several degenerative diseases, including multisystem proteinopathy (MSP-1) and amyotrophic lateral sclerosis. However, patients with VCP mutations vary widely in their pathology and clinical penetrance, making it difficult to devise e...
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| Publicado no: | Dis Model Mech |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8325010/ https://ncbi.nlm.nih.gov/pubmed/34160014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.048603 |
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