RNA m(6)A modification orchestrates a LINE-1–host interaction that facilitates retrotransposition and contributes to long gene vulnerability

The molecular basis underlying the interaction between retrotransposable elements (RTEs) and the human genome remains poorly understood. Here, we profiled N(6)-methyladenosine (m(6)A) deposition on nascent RNAs in human cells by developing a new method MINT-Seq, which revealed that many classes of R...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Xiong, Feng, Wang, Ruoyu, Lee, Joo-Hyung, Li, Shenglan, Chen, Shin-Fu, Liao, Zian, Hasani, Lana Al, Nguyen, Phuoc T., Zhu, Xiaoyu, Krakowiak, Joanna, Lee, Dung-Fang, Han, Leng, Tsai, Kuang-Lei, Liu, Ying, Li, Wenbo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324889/
https://ncbi.nlm.nih.gov/pubmed/34108665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-021-00515-8
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