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Enhancer RNAs in cancer: regulation, mechanisms and therapeutic potential

Enhancers are distal genomic elements critical for gene regulation and cell identify control during development and diseases. Many human cancers were found to associate with enhancer malfunction, due to genetic and epigenetic alterations, which in some cases directly drive tumour growth. Conventiona...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:RNA Biol
Hauptverfasser: Lee, Joo-Hyung, Xiong, Feng, Li, Wenbo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567500/
https://ncbi.nlm.nih.gov/pubmed/31916476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1712895
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