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Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells

Ischemia is a major cause of kidney damage. Proximal tubular epithelial cells (PTECs) are highly susceptible to ischemic insults that frequently cause acute kidney injury (AKI), a potentially life-threatening condition with high mortality. Accumulating evidence has identified altered mitochondrial f...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Haschler, Timo N., Horsley, Harry, Balys, Monika, Anderson, Glenn, Taanman, Jan-Willem, Unwin, Robert J., Norman, Jill T.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324880/
https://ncbi.nlm.nih.gov/pubmed/34330933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94185-6
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