Cargando...
Glibenclamide depletes ATP in renal proximal tubular cells by interfering with mitochondrial metabolism
1. Sulfonylurea drugs, like glibenclamide, stimulate insulin secretion by blocking ATP-sensitive potassium channels on pancreatic beta cells. Renal tubular epithelial cells possess a different class of K(ATP) channels with much lower affinities for sulfonylurea drugs, necessitating the use of microm...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2005
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576225/ https://ncbi.nlm.nih.gov/pubmed/15912128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706275 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|