Glibenclamide depletes ATP in renal proximal tubular cells by interfering with mitochondrial metabolism

1. Sulfonylurea drugs, like glibenclamide, stimulate insulin secretion by blocking ATP-sensitive potassium channels on pancreatic beta cells. Renal tubular epithelial cells possess a different class of K(ATP) channels with much lower affinities for sulfonylurea drugs, necessitating the use of microm...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Engbersen, Richard, Masereeuw, Rosalinde, van Gestel, Miriam A, van der Logt, Elise M J, Smits, Paul, Russel, Frans G M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576225/
https://ncbi.nlm.nih.gov/pubmed/15912128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706275
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky