Differential regulation of the platelet GPIb-IX complex by anti-GPIbβ antibodies

BACKGROUND: Platelets’ initial recognition of endothelial damage proceeds through the interaction between collagen, plasma von Willebrand factor (VWF), and the platelet glycoprotein (GP)Ib-IX complex (CD42). GPIb-IX complex consists of one GPIbα, one GPIX, and two GPIbβ subunits. Once platelets are...

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Bibliographic Details
Published in:J Thromb Haemost
Main Authors: Quach, M. Edward, Chen, Wenchun, Wang, Yingchun, Deckmyn, Hans, Lanza, Francois, Nieswandt, Bernhard, Li, Renhao
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324530/
https://ncbi.nlm.nih.gov/pubmed/33915031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15359
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