Biosynthesis and intracellular post-translational processing of normal and mutant platelet glycoprotein GPIb-IX.

The multisubunit leucine-rich glycoprotein (GP) Ib-IX-V complex mediates von Willebrand factor-dependent platelet adhesion at sites of blood-vessel injury. Molecular defects of this receptor are reported to cause the Bernard-Soulier haemorrhagic disorder. To gain insight into the mechanisms controll...

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Dettagli Bibliografici
Autori principali: Ulsemer, P, Strassel, C, Baas, M J, Salamero, J, Chasserot-Golaz, S, Cazenave, J P, De La Salle, C, Lanza, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222061/
https://ncbi.nlm.nih.gov/pubmed/11513727
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