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Ligand Conformational Flexibility Enables Enantioselective Tertiary C–B Bond Formation in the Phosphonate-Directed Catalytic Asymmetric Alkene Hydroboration

Conformationally flexible ancillary ligands have been widely used in transition metal catalysis. However, the benefits of using flexible ligands are often not well understood. We performed DFT and experimental studies to elucidate the mechanisms and the roles of conformationally flexible TADDOL-deri...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Shao, Huiling, Chakrabarty, Suman, Qi, Xiaotian, Takacs, James M., Liu, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324071/
https://ncbi.nlm.nih.gov/pubmed/33750118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c01303
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