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EZH2-targeted therapies in cancer: hype or a reality

Next-generation genomic sequencing has identified multiple novel molecular alterations in cancer. Since the identification of DNA methylation and histone modification, it has become evident that genes encoding epigenetic modifiers that locally and globally regulate gene expression play a crucial rol...

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Publicat a:Cancer Res
Autors principals: Eich, Marie-Lisa, Athar, Mohammad, Ferguson, James E., Varambally, Sooryanarayana
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323716/
https://ncbi.nlm.nih.gov/pubmed/32978169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-2147
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