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Targeting EZH2 for Cancer Therapy: Progress and Perspective

Enhancer of Zeste Homolog 2 (EZH2) is the core component of the polycomb repressive complex 2 (PRC2), possessing the enzymatic activity in generating di/tri-methylated lysine 27 in histone H3. EZH2 has important roles during early development, and its dysregulation is heavily linked to oncogenesis i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Protein Pept Sci
Prif Awduron: Li, Chi Han, Chen, Yangchao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Bentham Science Publishers 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997953/
https://ncbi.nlm.nih.gov/pubmed/25854924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389203716666150409100233
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