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Targeting EZH2 for Cancer Therapy: Progress and Perspective
Enhancer of Zeste Homolog 2 (EZH2) is the core component of the polycomb repressive complex 2 (PRC2), possessing the enzymatic activity in generating di/tri-methylated lysine 27 in histone H3. EZH2 has important roles during early development, and its dysregulation is heavily linked to oncogenesis i...
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| Publicado no: | Curr Protein Pept Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4997953/ https://ncbi.nlm.nih.gov/pubmed/25854924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389203716666150409100233 |
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