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Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions
Although glucose, through pentose phosphate pathway (PPP), is the main source to generate NADPH, solid tumors are often deprived of glucose, hence alternative metabolic pathways to maintain NADPH homeostasis in cancer cells are required. Here, we report that lactate and glutamine support NADPH produ...
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| Izdano u: | Redox Biol |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8321918/ https://ncbi.nlm.nih.gov/pubmed/34293554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102065 |
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