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Central role of lactate and proton in cancer cell resistance to glucose deprivation and its clinical translation

Targeting common weaknesses of cancer is an important strategy for cancer therapy. Glucose is a nutrient that maintains essential cellular metabolism, supporting cancer cell survival, growth and proliferation. Depriving glucose rapidly kills cancer cells. Most cancer cells possess a feature called W...

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Bibliografske podrobnosti
izdano v:Signal Transduct Target Ther
Main Authors: Hu, Xun, Chao, Ming, Wu, Hao
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661620/
https://ncbi.nlm.nih.gov/pubmed/29263910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2016.47
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