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Recurrent glucose deprivation leads to the preferential use of lactate by neurons in the ventromedial hypothalamus

Increased GABAergic output in the ventromedial hypothalamus (VMH) contributes to counterregulatory failure in recurrently hypoglycemic (RH) rats, and lactate, an alternate fuel source in the brain, contributes to this phenomenon. The current study assessed whether recurring bouts of glucose deprivat...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Shah, Maitreyee, Addison, Augustina, Wang, Peili, Zhu, Wanling, Chan, Owen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580165/
https://ncbi.nlm.nih.gov/pubmed/30888861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00468.2018
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