Downregulation of DUOX1 function contributes to aging-related impairment of innate airway injury responses and accelerated senile emphysema

Aging is associated with a gradual loss of lung function due to increased cellular senescence, decreased regenerative capacity, and impaired innate host defense. One important aspect of innate airway epithelial host defense to nonmicrobial triggers is the secretion of alarmins such as IL-33 and acti...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Physiol Lung Cell Mol Physiol
Päätekijät: Schiffers, Caspar, Lundblad, Lennart K. A., Hristova, Milena, Habibovic, Aida, Dustin, Christopher M., Daphtary, Nirav, Aliyeva, Minara, Seward, David J., Janssen-Heininger, Yvonne M. W., Wouters, Emiel F. M., Reynaert, Niki L., van der Vliet, Albert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2021
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321859/
https://ncbi.nlm.nih.gov/pubmed/33951398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00021.2021
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