CHCHD10 is involved in the development of Parkinson’s disease caused by CHCHD2 loss-of-function mutation p.T61I

Previously we identified the p.Thr61Ile mutation in coiled-coil-helix-coiled-coil-helix domain containing 2 (CHCHD2) in a Chinese family with autosomal dominant Parkinson’s disease. But the mechanism is still unclear. In this study, we explored the effects of CHCHD2 p.Thr61Ile mutation in cells and...

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Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Mao, Chengyuan, Wang, Herui, Luo, Haiyang, Zhang, Shuyu, Xu, Huisha, Zhang, Shuo, Rosenblum, Jared, Wang, Zhilei, Zhang, Qi, Tang, Mibo, Shepard, Matthew J., Wang, Xiang, Wang, Yaohe, Zhuang, Zhengping, Shi, Changhe, Xu, Yuming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320701/
https://ncbi.nlm.nih.gov/pubmed/30530185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.10.020
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