Fatty acid oxidation contributes to IL-1β secretion in M2 macrophages and promotes macrophage-mediated tumor cell migration

Tumor-associated macrophages (TAMs) are predominantly M2 phenotype in solid cancers including hepatocellular carcinoma (HCC). Though differentiation of M2 macrophages has been recently linked to fatty acid oxidation (FAO), whether FAO plays a role in functional maintenance of M2 macrophages is still...

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發表在:Mol Immunol
Main Authors: Zhang, Qi, Wang, Herui, Mao, Chengyuan, Sun, Mitchell, Dominah, Gifty, Chen, Liyuan, Zhuang, Zhengping
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801116/
https://ncbi.nlm.nih.gov/pubmed/29248877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.12.011
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