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Fatty acid oxidation contributes to IL-1β secretion in M2 macrophages and promotes macrophage-mediated tumor cell migration

Tumor-associated macrophages (TAMs) are predominantly M2 phenotype in solid cancers including hepatocellular carcinoma (HCC). Though differentiation of M2 macrophages has been recently linked to fatty acid oxidation (FAO), whether FAO plays a role in functional maintenance of M2 macrophages is still...

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Détails bibliographiques
Publié dans:Mol Immunol
Auteurs principaux: Zhang, Qi, Wang, Herui, Mao, Chengyuan, Sun, Mitchell, Dominah, Gifty, Chen, Liyuan, Zhuang, Zhengping
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801116/
https://ncbi.nlm.nih.gov/pubmed/29248877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.12.011
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