Fatty acid oxidation contributes to IL-1β secretion in M2 macrophages and promotes macrophage-mediated tumor cell migration

Tumor-associated macrophages (TAMs) are predominantly M2 phenotype in solid cancers including hepatocellular carcinoma (HCC). Though differentiation of M2 macrophages has been recently linked to fatty acid oxidation (FAO), whether FAO plays a role in functional maintenance of M2 macrophages is still...

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Pubblicato in:Mol Immunol
Autori principali: Zhang, Qi, Wang, Herui, Mao, Chengyuan, Sun, Mitchell, Dominah, Gifty, Chen, Liyuan, Zhuang, Zhengping
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801116/
https://ncbi.nlm.nih.gov/pubmed/29248877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.12.011
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