CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson’s disease

Mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson’s disease (PD). Carboxyl terminus of Hsp70-interacting protein (CHIP) is a key regulator of mitochondrial dynamics, and mutations in CHIP or deficits in its expression have been associated with various neurological diseas...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Aging (Albany NY)
Autori principali: Hu, Zhengwei, Mao, Chengyuan, Wang, Hui, Zhang, Zhongxian, Zhang, Shuo, Luo, Haiyang, Tang, Mibo, Yang, Jing, Yuan, Yanpeng, Wang, Yanlin, Liu, Yutao, Fan, Liyuan, Zhang, Qimeng, Yao, Dabao, Liu, Fen, Schisler, Jonathan C., Shi, Changhe, Xu, Yuming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals 2021
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7834979/
https://ncbi.nlm.nih.gov/pubmed/33472166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202389
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