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TRPM2 promotes neurotoxin MPP(+)/MPTP-induced cell death
In neurons, Ca(2+) is essential for a variety of physiological processes that regulate gene transcription to neuronal growth and their survival. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridinium ions (MPP(+)), are potent neurotoxins that selectively destroys the dop...
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| Publié dans: | Mol Neurobiol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5468501/ https://ncbi.nlm.nih.gov/pubmed/27957685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-0338-9 |
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