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Regional brain iron and gene expression provide insights into neurodegeneration in Parkinson’s disease

The mechanisms responsible for the selective vulnerability of specific neuronal populations in Parkinson’s disease are poorly understood. Oxidative stress secondary to brain iron accumulation is one postulated mechanism. We measured iron deposition in 180 cortical regions of 96 patients with Parkins...

詳細記述

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書誌詳細
出版年:Brain
主要な著者: Thomas, George E C, Zarkali, Angeliki, Ryten, Mina, Shmueli, Karin, Gil-Martinez, Ana Luisa, Leyland, Louise-Ann, McColgan, Peter, Acosta-Cabronero, Julio, Lees, Andrew J, Weil, Rimona S
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320305/
https://ncbi.nlm.nih.gov/pubmed/33704443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab084
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