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Regional brain iron and gene expression provide insights into neurodegeneration in Parkinson’s disease

The mechanisms responsible for the selective vulnerability of specific neuronal populations in Parkinson’s disease are poorly understood. Oxidative stress secondary to brain iron accumulation is one postulated mechanism. We measured iron deposition in 180 cortical regions of 96 patients with Parkins...

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Detalles Bibliográficos
Publicado en:Brain
Main Authors: Thomas, George E C, Zarkali, Angeliki, Ryten, Mina, Shmueli, Karin, Gil-Martinez, Ana Luisa, Leyland, Louise-Ann, McColgan, Peter, Acosta-Cabronero, Julio, Lees, Andrew J, Weil, Rimona S
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320305/
https://ncbi.nlm.nih.gov/pubmed/33704443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab084
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