Regional brain iron and gene expression provide insights into neurodegeneration in Parkinson’s disease

The mechanisms responsible for the selective vulnerability of specific neuronal populations in Parkinson’s disease are poorly understood. Oxidative stress secondary to brain iron accumulation is one postulated mechanism. We measured iron deposition in 180 cortical regions of 96 patients with Parkins...

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Dades bibliogràfiques
Publicat a:Brain
Autors principals: Thomas, George E C, Zarkali, Angeliki, Ryten, Mina, Shmueli, Karin, Gil-Martinez, Ana Luisa, Leyland, Louise-Ann, McColgan, Peter, Acosta-Cabronero, Julio, Lees, Andrew J, Weil, Rimona S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320305/
https://ncbi.nlm.nih.gov/pubmed/33704443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab084
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