Regional brain iron and gene expression provide insights into neurodegeneration in Parkinson’s disease

The mechanisms responsible for the selective vulnerability of specific neuronal populations in Parkinson’s disease are poorly understood. Oxidative stress secondary to brain iron accumulation is one postulated mechanism. We measured iron deposition in 180 cortical regions of 96 patients with Parkins...

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Enregistré dans:
Détails bibliographiques
Publié dans:Brain
Auteurs principaux: Thomas, George E C, Zarkali, Angeliki, Ryten, Mina, Shmueli, Karin, Gil-Martinez, Ana Luisa, Leyland, Louise-Ann, McColgan, Peter, Acosta-Cabronero, Julio, Lees, Andrew J, Weil, Rimona S
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320305/
https://ncbi.nlm.nih.gov/pubmed/33704443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab084
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