Synthesis and Biological Evaluation of Thiazole-Based Derivatives as Potential Acetylcholinesterase Inhibitors

[Image: see text] Nineteen new thiazole-based derivatives were synthesized and their structures characterized with analytical and spectral data. The in vitro assessment of their acetylcholinesterase (AChE) inhibitory activity revealed that compounds 10 and 16 produced potent AChE inhibitory activiti...

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Bibliographic Details
Published in:ACS Omega
Main Authors: Hemaida, Aya Y., Hassan, Ghada S., Maarouf, Azza R., Joubert, Jacques, El-Emam, Ali A.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2021
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320107/
https://ncbi.nlm.nih.gov/pubmed/34337258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c02549
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