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Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors

A novel series of thiazole-naphthalene derivatives as tubulin polymerisation inhibitors were designed, synthesised, and evaluated for the anti-proliferative activities. The majority of the tested compounds exhibited moderate to potent antiproliferative activity on the MCF-7 and A549 cancer cell line...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Wang, Guangcheng, Liu, Wenjing, Fan, Meiyan, He, Min, Li, Yongjun, Peng, Zhiyun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317958/
https://ncbi.nlm.nih.gov/pubmed/34309466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1958213
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