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Cryo-EM reveals conformational flexibility in apo DNA polymerase ζ

The translesion synthesis (TLS) DNA polymerases Rev1 and Polζ function together in DNA lesion bypass during DNA replication, acting as nucleotide inserter and extender polymerases, respectively. While the structural characterization of the Saccharomyces cerevisiae Polζ in its DNA-bound state has ill...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Du Truong, Chloe, Craig, Theodore A., Cui, Gaofeng, Botuyan, Maria Victoria, Serkasevich, Rachel A., Chan, Ka-Yi, Mer, Georges, Chiu, Po-Lin, Kumar, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319531/
https://ncbi.nlm.nih.gov/pubmed/34174285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100912
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