Cryo-EM reveals conformational flexibility in apo DNA polymerase ζ

The translesion synthesis (TLS) DNA polymerases Rev1 and Polζ function together in DNA lesion bypass during DNA replication, acting as nucleotide inserter and extender polymerases, respectively. While the structural characterization of the Saccharomyces cerevisiae Polζ in its DNA-bound state has ill...

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Vydáno v:J Biol Chem
Hlavní autoři: Du Truong, Chloe, Craig, Theodore A., Cui, Gaofeng, Botuyan, Maria Victoria, Serkasevich, Rachel A., Chan, Ka-Yi, Mer, Georges, Chiu, Po-Lin, Kumar, Rajiv
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319531/
https://ncbi.nlm.nih.gov/pubmed/34174285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100912
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