Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis

Voltage dependent anion channel 2 (VDAC2) is an outer mitochondrial membrane porin known to play a significant role in apoptosis and calcium signaling. Abnormalities in calcium homeostasis often leads to electrical and contractile dysfunction and can cause dilated cardiomyopathy and heart failure. H...

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Yayımlandı:Nat Commun
Asıl Yazarlar: Shankar, Thirupura S., Ramadurai, Dinesh K. A., Steinhorst, Kira, Sommakia, Salah, Badolia, Rachit, Thodou Krokidi, Aspasia, Calder, Dallen, Navankasattusas, Sutip, Sander, Paulina, Kwon, Oh Sung, Aravamudhan, Aishwarya, Ling, Jing, Dendorfer, Andreas, Xie, Changmin, Kwon, Ohyun, Cheng, Emily H. Y., Whitehead, Kevin J., Gudermann, Thomas, Richardson, Russel S., Sachse, Frank B., Schredelseker, Johann, Spitzer, Kenneth W., Chaudhuri, Dipayan, Drakos, Stavros G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319341/
https://ncbi.nlm.nih.gov/pubmed/34321484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24869-0
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