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Stereoselective Synthesis of β-Branched Aromatic α-Amino Acids via Biocatalytic Dynamic Kinetic Resolution

β-branched noncanonical amino acids are valuable molecules in modern drug development efforts. However, they are still challenging to prepare due to the need to set multiple stereocenters in a stereoselective fashion and contemporary methods to achieve this often relies on the use of rare transition...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Li, Fuzhuo, Yang, Li-Cheng, Zhang, Jingyang, Chen, Jason S., Renata, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319157/
https://ncbi.nlm.nih.gov/pubmed/34056805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202105656
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