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Mitochondrial derived vesicles compensate for loss of LC3-mediated mitophagy

Mitochondria are critical metabolic and signaling hubs and dysregulated mitochondrial homeostasis is implicated in many diseases. Degradation of damaged mitochondria by selective GABARAP/LC3-dependent macro-autophagy (mitophagy) is critical for maintaining mitochondrial homeostasis. To identify alte...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Towers, Christina G, Wodetzki, Darya K, Thorburn, Jacqueline, Smith, Katharine R, Caino, M. Cecilia, Thorburn, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319140/
https://ncbi.nlm.nih.gov/pubmed/34171288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2021.06.003
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