Iron loss triggers mitophagy through induction of mitochondrial ferritin

Mitochondrial quality is controlled by the selective removal of damaged mitochondria through mitophagy. Mitophagy impairment is associated with aging and many pathological conditions. An iron loss induced by iron chelator triggers mitophagy by a yet unknown mechanism. This type of mitophagy may have...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Hara, Yuichi, Yanatori, Izumi, Tanaka, Atsushi, Kishi, Fumio, Lemasters, John J, Nishina, Sohji, Sasaki, Kyo, Hino, Keisuke
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645172/
https://ncbi.nlm.nih.gov/pubmed/32975364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050202
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