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Autophagy-dependent cancer cells circumvent loss of the upstream regulator RB1CC1/FIP200 and loss of LC3 conjugation by similar mechanisms

Macroautophagy/autophagy degrades proteins and organelles to generate macromolecular building blocks. As such, some cancer cells are particularly dependent on autophagy. In a previous paper, we found that even highly autophagy-dependent cancer cells can adapt to circumvent autophagy inhibition. Howe...

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Bibliografische gegevens
Gepubliceerd in:Autophagy
Hoofdauteurs: Towers, Christina G., Wodetzki, Darya, Thorburn, Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469620/
https://ncbi.nlm.nih.gov/pubmed/32160093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1741204
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